One in 500 men carry extra sex chromosome, research suggests
Twice as many men carry an extra sex chromosome as previously thought, according to researchers who called for more genetic testing to identify people at greater risk of related medical problems.
Research on more than 200,000 men enrolled with the UK Biobank suggests that about one in 500 in the general population has an extra X or Y chromosome, double the number found in earlier work, though only a fraction are likely to be aware of it.
While most men have one X and one Y chromosome, some are born XXY or XYY, putting them at increased risk of health issues ranging from type 2 diabetes, blocked blood vessels and chronic obstructive pulmonary disease (COPD), a lung condition, the study found.
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